With the move of Glasgow to center and the insertion of Bryant into the lineup at LG, it means a few changes may be in order. Bryant, less the fleet of foot and more the very large, squatty man that is more of a hitter and less of a reacher, probably indicates that Michigan will go to more of a traditional man blocking scheme. Add on that Glasgow isn't the quickest of players for the center position in a stretch run team, and it's likely that Michigan will be running less zone stretch and more gap blocking type activities (with the occasional inside zone mixed in). Because of that, it seems a good time to add onto Power O blocking piece and look at how Iso is blocked and what the RB is looking at.
Note here that this is a strongside Iso. The center comes off his combo block almost instantly because of the aggressive nature of Notre Dame's LBs. He is letting the LB take himself out of the play, essentially combo blocking to him without doubling at the point of attack.
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Follow the link the Maize n Brew to learn more about the Isolation play.